Verrucous carcinoma arising in a giant condyloma acuminata (Buschkelowenstein Tumour): ten-year follow-up.

Dear Editor, Giant condyloma acuminate (GCA) fi rst described by Buschke, also known as Buschke-Löwenstein tumour (BLT), is a slow growing, semi malignant neoplasm of the external genitalia and perianal region that has a recurrence tendency.1 Inspite of its histologically benign appearance, BLT clinically behaves in a malignant fashion, destroying adjacent tissues, and is reported as an entity intermediate between an ordinary condyloma acuminatum and squamouscell carcinoma (SCC).2 BLT is likely to be a step into a spectrum of diseases that include malignant degeneration.1 Verrucous carcinoma (VC) was fi rst described as a distinct well-differentiated variety of SCC by Ackerman.2 VC tends to appear mainly in oropharynx, genitalia and soles, although it may occur anywhere on the skin. Thus, VC has been known by several different names in relation to the anatomical site of the lesion.3 Different treatment modalities were applied on those patients with VC.1,3 A case of BLT in the perianal region and secondary VC, that was treated only by surgical excision and was followed-up for 10 years, is presented and the literature is reviewed in this letter.